Grey’s Anatomyis one of those shows that many of us simply cannot get enough of.
In 2019, ABC renewed the series for a mind-blowing 16th and 17th seasons (viaTV Line).
Even before this renewal, the show was already the internet’slongest-running primetimescripted show.

It’s easy to see why so many viewers are completely obsessed.
But where were these actors prior to theirGrey’s Anatomyfame?
Here is the lowdown on the biggestGrey’s Anatomystars before all the celebrity.

Since beginning the show, Pompeo has rocketed to fame.
However, Pompeo didn’t always think she’d have a career in acting.
That’s what I want to do.'"

Despite loving the showbiz industry from a young age, her shyness almost got the better of her.
Nevertheless, Pompeo followed her dreams.
But Oh almost didn’t get to have her fabulous acting career.

“My parents at that time really looked down on the arts,” she explained.
For her parents, acting was apparently “one step above prostitution.”
Luckily, Oh’s parents seem to have come around to their daughter’s career choice.

The actress left the show during the its sixth season, as noted byEntertainment Tonight.
But what was life like for Heigl before she found fame as Izzie?
Well, it turns out, Heigl’s career kicked off at a fairly young age.

Soon enough, she was chosen to pose for a Sears catalogue and she started acting.
However, the Heigl family was dealing with some awful events around that time.
“My parents became shells of themselves,” she said.

“My 12-year-old sister and I were just sort of wading through everyone else’s grief.”
So, who was Chambers before he shot to fame?
In 2014, the star spoke toUs Weeklyand offered up some details about his past.

Chambers spent his childhood in Ohio with “cool parents” who were “deputy sheriffs.”
Instead, the star was once set to become a circus performer!
“I did birthday parties on weekends,” he explained.

“So I started off in old school vaudeville actually.”
Before joining the series, Pickens appeared in a few well-known TV shows and films.
Pickens' foray into acting began with stage roles.

He also starred in the Roundabout Theater’s production ofA Raisin in the Sun.
It was only in the ’90s that Pickens made the move to Hollywood and his TV career took off.
Despite his memorable performance on the show, Williams wasn’t always keen on acting as a career.

In fact, before acting, he was a high school teacher.
“Then I moved to a suburban area and had a healthy public school experience.
I found this incredible chasm between two of the many Americas we have.”

No wonder Dr. Bailey was such a great singer!
What manyGrey’s Anatomyfans fail to realize is that McKidd is actually a fully-fledged Scotsman!
He evenchanges his accentfor the show.

It turns out, he had a pretty unglamorous Scottish upbringing before his film career took off.
It turns out, there were times when the McKidd family could barely afford dinner.
It’s pretty clear that McKidd has come a long way since those difficult times in Scotland!

But what was she like before joining the show?
And pretty soon, she had a few moreimpressive creditsunder her belt, including roles inEverwoodandMad Men.
She revealed toTV Guidethat she auditioned for two other roles on the show before getting cast!

Her first audition was for Nurse Rose, but the role went to Lauren Stamile.
Next, she auditioned to play Sadie, but this part went to Melissa George.
Just three months after that audition, theGrey’steam offered her a three-episode arch as Arizona Robbins.
Despite only being on the show until 2012, Dane remains one of the most popular and memorable characters.
But what was life like for McSteamy beforeGrey’s Anatomy?
Well, it seems that he only really had the chance to play bit characters before.
His character wasn’t in every episode, but Dane was becoming a little better known by TV fans.
Finally, he won the role of Dr. Mark Sloan, which would change his career.
Apparently, the gig started as aguest role.
Luckily, the writers must have seen his potential, and the then-futureEuphoriastar quickly became central to the story.
Eventually, Luddington attended the New York Film Academy.
However, George wasn’t always planning on an acting career.
According toUVA Today,George came very close to becoming a lawyer.